Role of Sphingosine Kinase/S1P Axis in ECM Remodeling of Cardiac Cells Elicited by Relaxin

The initiation and progression of heart failure is linked to adverse cardiac remodeling of the extracellular matrix (ECM) during disease mainly through the deregulation of myocardial metalloproteinases (MMPs). Relaxin (RLX), a peptide hormone acting as a physiological cardiac effector, is a key regu...

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Bibliografski detalji
Izdano u:Mol Endocrinol
Glavni autori: Frati, Alessia, Ricci, Barbara, Pierucci, Federica, Nistri, Silvia, Bani, Daniele, Meacci, Elisabetta
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2015
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414773/
https://ncbi.nlm.nih.gov/pubmed/25415609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1201
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