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Role of Sphingosine Kinase/S1P Axis in ECM Remodeling of Cardiac Cells Elicited by Relaxin

The initiation and progression of heart failure is linked to adverse cardiac remodeling of the extracellular matrix (ECM) during disease mainly through the deregulation of myocardial metalloproteinases (MMPs). Relaxin (RLX), a peptide hormone acting as a physiological cardiac effector, is a key regu...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Frati, Alessia, Ricci, Barbara, Pierucci, Federica, Nistri, Silvia, Bani, Daniele, Meacci, Elisabetta
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414773/
https://ncbi.nlm.nih.gov/pubmed/25415609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1201
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