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Mitochondrial targeting by dichloroacetate improves outcome following hemorrhagic shock
Hemorrhagic shock is a leading cause of death in people under the age of 45 and accounts for almost half of trauma-related deaths. In order to develop a treatment strategy based on potentiating mitochondrial function, we investigated the effect of the orphan drug dichloroacetate (DCA) on survival in...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5453974/ https://ncbi.nlm.nih.gov/pubmed/28572638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02495-5 |
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