MicroRNA-150 modulates intracellular Ca(2+) levels in naïve CD8(+) T cells by targeting TMEM20

Regulation of intracellular Ca(2+) signaling is a major determinant of CD8(+) T cell responsiveness, but the mechanisms underlying this regulation of Ca(2+) levels, especially in naïve CD8(+) T cells, are not fully defined. Here, we showed that microRNA-150 (miR-150) controls intracellular Ca(2+) le...

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Publicat a:Sci Rep
Autors principals: Kim, Tae-Don, Jung, Hong-Ryul, Seo, Sang-Hwan, Oh, Se-Chan, Ban, Youngho, Tan, Xiaoxia, Min Kim, Jung, Hyun Lee, Sang, Koh, Duk-Su, Jung, Haiyoung, Park, Young-Jun, Ran Yoon, Suk, Doh, Junsang, Ha, Sang-Jun, Choi, Inpyo, Greenberg, Philip D.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453935/
https://ncbi.nlm.nih.gov/pubmed/28572627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02697-x
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