Tentonin 3/TMEM150C senses blood pressure changes in the aortic arch

The baroreceptor reflex is a powerful neural feedback that regulates arterial pressure (AP). Mechanosensitive channels transduce pulsatile AP to electrical signals in baroreceptors. Here we show that tentonin 3 (TTN3/TMEM150C), a cation channel activated by mechanical strokes, is essential for detec...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Lu, Huan-Jun, Nguyen, Thien-Luan, Hong, Gyu-Sang, Pak, Sungmin, Kim, Hyesu, Kim, Hyungsup, Kim, Dong-Yoon, Kim, Sung-Yon, Shen, Yiming, Ryu, Pan Dong, Lee, Mi-Ock, Oh, Uhtaek
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324181/
https://ncbi.nlm.nih.gov/pubmed/32484458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133798
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