Epithelial Gpr116 regulates pulmonary alveolar homeostasis via G(q/11) signaling

Pulmonary function is dependent upon the precise regulation of alveolar surfactant. Alterations in pulmonary surfactant concentrations or function impair ventilation and cause tissue injury. Identification of the molecular pathways that sense and regulate endogenous alveolar surfactant concentration...

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Publicado en:JCI Insight
Autores principales: Brown, Kari, Filuta, Alyssa, Ludwig, Marie-Gabrielle, Seuwen, Klaus, Jaros, Julian, Vidal, Solange, Arora, Kavisha, Naren, Anjaparavanda P., Kandasamy, Kathirvel, Parthasarathi, Kaushik, Offermanns, Stefan, Mason, Robert J., Miller, William E., Whitsett, Jeffrey A., Bridges, James P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453702/
https://ncbi.nlm.nih.gov/pubmed/28570277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93700
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