Epithelial Gpr116 regulates pulmonary alveolar homeostasis via G(q/11) signaling

Pulmonary function is dependent upon the precise regulation of alveolar surfactant. Alterations in pulmonary surfactant concentrations or function impair ventilation and cause tissue injury. Identification of the molecular pathways that sense and regulate endogenous alveolar surfactant concentration...

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Pubblicato in:JCI Insight
Autori principali: Brown, Kari, Filuta, Alyssa, Ludwig, Marie-Gabrielle, Seuwen, Klaus, Jaros, Julian, Vidal, Solange, Arora, Kavisha, Naren, Anjaparavanda P., Kandasamy, Kathirvel, Parthasarathi, Kaushik, Offermanns, Stefan, Mason, Robert J., Miller, William E., Whitsett, Jeffrey A., Bridges, James P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453702/
https://ncbi.nlm.nih.gov/pubmed/28570277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93700
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