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Suppression of asparaginyl endopeptidase attenuates breast cancer-induced bone pain through inhibition of neurotrophin receptors

OBJECTIVE: Cancer-induced bone pain is a common clinical problem in breast cancer patients with bone metastasis. However, the mechanisms driving cancer-induced bone pain are poorly known. Recent studies show that a novel protease, asparaginyl endopeptidase (AEP) plays crucial roles in breast cancer...

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Detalhes bibliográficos
Publicado no:Mol Pain
Main Authors: Yao, Peng, Ding, Yuanyuan, Han, Zhenkai, Mu, Ying, Hong, Tao, Zhu, Yongqiang, Li, Hongxi
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453632/
https://ncbi.nlm.nih.gov/pubmed/28554249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806917708127
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