Combining inferred regulatory and reconstructed metabolic networks enhances phenotype prediction in yeast

Gene regulatory and metabolic network models have been used successfully in many organisms, but inherent differences between them make networks difficult to integrate. Probabilistic Regulation Of Metabolism (PROM) provides a partial solution, but it does not incorporate network inference and underpe...

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Udgivet i:PLoS Comput Biol
Main Authors: Wang, Zhuo, Danziger, Samuel A., Heavner, Benjamin D., Ma, Shuyi, Smith, Jennifer J., Li, Song, Herricks, Thurston, Simeonidis, Evangelos, Baliga, Nitin S., Aitchison, John D., Price, Nathan D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453602/
https://ncbi.nlm.nih.gov/pubmed/28520713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005489
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