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Combining inferred regulatory and reconstructed metabolic networks enhances phenotype prediction in yeast

Gene regulatory and metabolic network models have been used successfully in many organisms, but inherent differences between them make networks difficult to integrate. Probabilistic Regulation Of Metabolism (PROM) provides a partial solution, but it does not incorporate network inference and underpe...

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Publicat a:PLoS Comput Biol
Autors principals: Wang, Zhuo, Danziger, Samuel A., Heavner, Benjamin D., Ma, Shuyi, Smith, Jennifer J., Li, Song, Herricks, Thurston, Simeonidis, Evangelos, Baliga, Nitin S., Aitchison, John D., Price, Nathan D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453602/
https://ncbi.nlm.nih.gov/pubmed/28520713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005489
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