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Combining inferred regulatory and reconstructed metabolic networks enhances phenotype prediction in yeast

Gene regulatory and metabolic network models have been used successfully in many organisms, but inherent differences between them make networks difficult to integrate. Probabilistic Regulation Of Metabolism (PROM) provides a partial solution, but it does not incorporate network inference and underpe...

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Библиографические подробности
Опубликовано в: :PLoS Comput Biol
Главные авторы: Wang, Zhuo, Danziger, Samuel A., Heavner, Benjamin D., Ma, Shuyi, Smith, Jennifer J., Li, Song, Herricks, Thurston, Simeonidis, Evangelos, Baliga, Nitin S., Aitchison, John D., Price, Nathan D.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453602/
https://ncbi.nlm.nih.gov/pubmed/28520713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005489
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