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Nanoagonist-mediated endothelial tight junction opening: A strategy for safely increasing brain drug delivery in mice

Even though opening endothelial tight junctions is an efficient way to up-regulate brain drug delivery, the extravasation of blood-borne components from the compromised tight junctions can result in adverse consequences such as edema and neuronal injuries. In this work, we developed a nanoagonist th...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Gao, Xihui, Wang, Yuan-Cheng, Liu, Yikang, Yue, Qi, Liu, Zining, Ke, Mengjing, Zhao, Shengyuan, Li, Cong
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453461/
https://ncbi.nlm.nih.gov/pubmed/27342320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16656198
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