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Zwitterionic Micelles Efficiently Deliver Oral Insulin Without Opening Tight Junctions

Oral delivery of protein drugs is considered a life-changing solution for patients who require regular needle injections. However, clinical translation of oral protein formulations has been hampered by inefficient penetration of drugs through the intestinal mucus and epithelial cell layer, leading t...

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Bibliografiske detaljer
Udgivet i:Nat Nanotechnol
Main Authors: Han, Xiangfei, Lu, Yang, Xie, Jinbing, Zhang, Ershuai, Zhu, Hui, Du, Hong, Wang, Ke, Song, Boyi, Yang, Chengbiao, Shi, Yuanjie, Cao, Zhiqiang
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7534179/
https://ncbi.nlm.nih.gov/pubmed/32483319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41565-020-0693-6
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