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Evaluation of [(18)F]MC225 as a PET radiotracer for measuring P-glycoprotein function at the blood–brain barrier in rats: Kinetics, metabolism, and selectivity
P-glycoprotein is a protective efflux transporter at the blood–brain barrier showing altered function in many neurological disorders. The purpose of this study was to validate [(18)F]MC225 as a radiotracer for measuring P-glycoprotein function with positron emission tomography. Three groups of Sprag...
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| Publicado no: | J Cereb Blood Flow Metab |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5453451/ https://ncbi.nlm.nih.gov/pubmed/27354093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16654493 |
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