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A microRNA-operated switch of asymmetric-to-symmetric cancer stem cell divisions

Defective asymmetric cell divisions of stem and progenitor cells are associated with tumorigenesis by a largely unknown mechanism. A signalling axis involving Snail, microRNA-146a and Numb is now shown to regulate the switch between symmetric and asymmetric cell division in colorectal cancer stem ce...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Cell Biol
Prif Awduron: Lerner, Robin G., Petritsch, Claudia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453176/
https://ncbi.nlm.nih.gov/pubmed/24576899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2924
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