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A microRNA-operated switch of asymmetric-to-symmetric cancer stem cell divisions
Defective asymmetric cell divisions of stem and progenitor cells are associated with tumorigenesis by a largely unknown mechanism. A signalling axis involving Snail, microRNA-146a and Numb is now shown to regulate the switch between symmetric and asymmetric cell division in colorectal cancer stem ce...
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| Publicado no: | Nat Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5453176/ https://ncbi.nlm.nih.gov/pubmed/24576899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2924 |
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