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Novel proapoptotic agent SM-1 enhances the inhibitory effect of 5-fluorouracil on colorectal cancer cells in vitro and in vivo

5-Fluorouracil (5-FU) is one of the most important agents used to treat colorectal cancer. However, the therapeutic effect of 5-FU on colon cancer is limited. SM-1 is a novel type of proapoptotic agent that directly activates procaspase-3 to caspase-3, leading to apoptosis in human cancer cells. The...

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Опубликовано в: :Oncol Lett
Главные авторы: Wang, Ying, Yuan, Shoujun, Li, Linna, Yang, Dexuan, Xu, Chengwang, Wang, Shanshan, Zhang, Danshen
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452999/
https://ncbi.nlm.nih.gov/pubmed/28599477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6043
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