Micheliolide Derivative DMAMCL Inhibits Glioma Cell Growth In Vitro and In Vivo

BACKGROUND: There is no highly effective chemotherapy for malignant gliomas to date. We found that dimethylaminomicheliolide (DMAMCL), a selective inhibitor of acute myeloid leukemia (AML) stem/progenitor cells, inhibited the growth of glioma cells. METHODS: The distribution of DMAMCL in brain was a...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: An, Yinghong, Guo, Wanjun, Li, Linna, Xu, Chengwang, Yang, Dexuan, Wang, Shanshan, Lu, Yaxin, Zhang, Quan, Zhai, Jiadai, Fan, Hongxia, Qiu, Chuanjiang, Qi, Jie, Chen, Yue, Yuan, Shoujun
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320118/
https://ncbi.nlm.nih.gov/pubmed/25658946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116202
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