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Selective Nrf2 Gene Deletion in the Rostral Ventrolateral Medulla Evokes Hypertension and Sympatho-Excitation in Mice

Nuclear factor E2-related factor 2 (Nrf2) is a master transcriptional regulator of redox homeostasis that impacts antioxidant gene expression. Central oxidative stress and reduced antioxidant enzyme expression in the rostral ventrolateral medulla (RVLM) contributed to sympatho-excitation in chronic...

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Bibliografiske detaljer
Udgivet i:Hypertension
Main Authors: Gao, Lie, Zimmerman, Matthew C., Biswal, Shyam, Zucker, Irving H.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452971/
https://ncbi.nlm.nih.gov/pubmed/28461605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09123
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