Clinical significance of the estrogen-modifying enzymes steroid sulfatase and estrogen sulfotransferase in epithelial ovarian cancer

17β-estradiol (E2) can contribute to the progression of epithelial ovarian cancer (EOC). Although the majority of patients with EOC are postmenopausal woman, when de novo estrogen production in the ovary has ceased, ovarian cancer cells remain exposed to estrogens synthesized locally in the cancer c...

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Udgivet i:Oncol Lett
Main Authors: Mungenast, Felicitas, Aust, Stefanie, Vergote, Ignace, Vanderstichele, Adriaan, Sehouli, Jalid, Braicu, Elena, Mahner, Sven, Castillo-Tong, Dan Cacsire, Zeillinger, Robert, Thalhammer, Theresia
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452883/
https://ncbi.nlm.nih.gov/pubmed/28588698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.5969
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