Ambivalent role of pFAK-Y397 in serous ovarian cancer-a study of the OVCAD consortium

BACKGROUND: Focal adhesion kinase (FAK) autophosphorylation seems to be a potential therapeutic target but little is known about the role and prognostic value of FAK and pFAK in epithelial ovarian cancer (EOC). Recently, we validated a gene signature classifying EOC patients into two subclasses and...

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Bibliographische Detailangaben
Hauptverfasser: Aust, Stefanie, Auer, Katharina, Bachmayr-Heyda, Anna, Denkert, Carsten, Sehouli, Jalid, Braicu, Ioana, Mahner, Sven, Lambrechts, Sandrina, Vergote, Ignace, Grimm, Christoph, Horvat, Reinhard, Castillo-Tong, Dan Cacsire, Zeillinger, Robert, Pils, Dietmar
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998046/
https://ncbi.nlm.nih.gov/pubmed/24655477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-67
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