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HIF1α is an independent prognostic factor for overall survival in advanced primary epithelial ovarian cancer – a study of the OVCAD Consortium

PURPOSE: Hypoxia is a common phenomenon encountered in solid cancers, leading to chemotherapy resistance and therefore to aggressiveness of the disease. The homeostatic response to hypoxia is mediated by hypoxiainducible factor-1 (HIF-1). The aim of this study was to investigate the impact of HIF1α...

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Bibliografiske detaljer
Main Authors: Braicu, Elena Ioana, Luketina, Hrvoje, Richter, Rolf, Cacsire Castillo-Tong, Dan, Lambrechts, Sandrina, Mahner, Sven, Concin, Nicole, Mentze, Monika, Zeillinger, Robert, Vergote, Ignace, Sehouli, Jalid
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166345/
https://ncbi.nlm.nih.gov/pubmed/25246800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S65373
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