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High-Fat Diet Feeding Alters Expression of Hepatic Drug-Metabolizing Enzymes in Mice
Medical conditions accompanying obesity often require drug therapy, but whether and how obesity alters the expression of drug-metabolizing enzymes and thus drug pharmacokinetics is poorly defined. Previous studies have shown that high-fat diet (HFD) feeding and subsequent obesity in mice lead to alt...
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| Publicado en: | Drug Metab Dispos |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5452677/ https://ncbi.nlm.nih.gov/pubmed/28442500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.075655 |
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