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High-Fat Diet Feeding Alters Expression of Hepatic Drug-Metabolizing Enzymes in Mice

Medical conditions accompanying obesity often require drug therapy, but whether and how obesity alters the expression of drug-metabolizing enzymes and thus drug pharmacokinetics is poorly defined. Previous studies have shown that high-fat diet (HFD) feeding and subsequent obesity in mice lead to alt...

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Pubblicato in:Drug Metab Dispos
Autori principali: Ning, Miaoran, Jeong, Hyunyoung
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452677/
https://ncbi.nlm.nih.gov/pubmed/28442500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.075655
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