Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells

BACKGROUND: Retroviral vectors are derived from wild-type retroviruses, can be used to study retrovirus-host interactions and are effective tools in gene and cell therapy. However, numerous cell types are resistant or less permissive to retrovirus infection due to the presence of active defense mech...

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Bibliographic Details
Published in:Retrovirology
Main Authors: Geis, Franziska K., Galla, Melanie, Hoffmann, Dirk, Kuehle, Johannes, Zychlinski, Daniela, Maetzig, Tobias, Schott, Juliane W., Schwarzer, Adrian, Goffinet, Christine, Goff, Stephen P., Schambach, Axel
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452410/
https://ncbi.nlm.nih.gov/pubmed/28569216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0358-1
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