Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells

BACKGROUND: Retroviral vectors are derived from wild-type retroviruses, can be used to study retrovirus-host interactions and are effective tools in gene and cell therapy. However, numerous cell types are resistant or less permissive to retrovirus infection due to the presence of active defense mech...

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Detalhes bibliográficos
Publicado no:Retrovirology
Main Authors: Geis, Franziska K., Galla, Melanie, Hoffmann, Dirk, Kuehle, Johannes, Zychlinski, Daniela, Maetzig, Tobias, Schott, Juliane W., Schwarzer, Adrian, Goffinet, Christine, Goff, Stephen P., Schambach, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452410/
https://ncbi.nlm.nih.gov/pubmed/28569216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0358-1
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