Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells

BACKGROUND: Retroviral vectors are derived from wild-type retroviruses, can be used to study retrovirus-host interactions and are effective tools in gene and cell therapy. However, numerous cell types are resistant or less permissive to retrovirus infection due to the presence of active defense mech...

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Veröffentlicht in:Retrovirology
Hauptverfasser: Geis, Franziska K., Galla, Melanie, Hoffmann, Dirk, Kuehle, Johannes, Zychlinski, Daniela, Maetzig, Tobias, Schott, Juliane W., Schwarzer, Adrian, Goffinet, Christine, Goff, Stephen P., Schambach, Axel
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452410/
https://ncbi.nlm.nih.gov/pubmed/28569216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0358-1
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