In-vivo monitoring of anti-folate therapy in arthritic rats using [(18)F]fluoro-PEG-folate and positron emission tomography

BACKGROUND: Folate receptor β (FRβ) is involved in facilitating cellular uptake of folates and anti-folates (such as methotrexate (MTX)). In rheumatoid arthritis, FRβ is expressed on synovial macrophages and recently has been explored as a biomarker for imaging in arthritic rats using the folate-bas...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Chandrupatla, Durga M. S. H., Jansen, Gerrit, Vos, Ricardo, Verlaan, Mariska, Chen, Qingshou, Low, Philip S., Windhorst, Albert D., Lammertsma, Adriaan A., van der Laken, Conny J., Molthoff, Carla F. M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452381/
https://ncbi.nlm.nih.gov/pubmed/28569209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1325-x
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