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Rotational restriction of nascent peptides as an essential element of co-translational protein folding: possible molecular players and structural consequences

BACKGROUND: A basic tenet of protein science is that all information about the spatial structure of proteins is present in their sequences. Nonetheless, many proteins fail to attain native structure upon experimental denaturation and refolding in vitro, raising the question of the specific role of c...

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Detalhes bibliográficos
Publicado no:Biol Direct
Main Authors: Sorokina, Irina, Mushegian, Arcady
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452302/
https://ncbi.nlm.nih.gov/pubmed/28569180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-017-0186-1
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