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Rotational restriction of nascent peptides as an essential element of co-translational protein folding: possible molecular players and structural consequences

BACKGROUND: A basic tenet of protein science is that all information about the spatial structure of proteins is present in their sequences. Nonetheless, many proteins fail to attain native structure upon experimental denaturation and refolding in vitro, raising the question of the specific role of c...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biol Direct
Prif Awduron: Sorokina, Irina, Mushegian, Arcady
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452302/
https://ncbi.nlm.nih.gov/pubmed/28569180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-017-0186-1
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