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Rotational restriction of nascent peptides as an essential element of co-translational protein folding: possible molecular players and structural consequences

BACKGROUND: A basic tenet of protein science is that all information about the spatial structure of proteins is present in their sequences. Nonetheless, many proteins fail to attain native structure upon experimental denaturation and refolding in vitro, raising the question of the specific role of c...

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Vydáno v:Biol Direct
Hlavní autoři: Sorokina, Irina, Mushegian, Arcady
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452302/
https://ncbi.nlm.nih.gov/pubmed/28569180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-017-0186-1
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