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Allosteric DNA nanoswitches for controlled release of a molecular cargo triggered by biological inputs
Here we demonstrate the rational design of a new class of DNA-based nanoswitches which are allosterically regulated by specific biological targets, antibodies and transcription factors, and are able to load and release a molecular cargo (i.e. doxorubicin) in a controlled fashion. In our first model...
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| Veröffentlicht in: | Chem Sci |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Royal Society of Chemistry
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5452262/ https://ncbi.nlm.nih.gov/pubmed/28572901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc03404g |
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