Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor.

Proteolytic cleavage of the von Willebrand factor subunit may be important for processing and/or function of the molecule and is altered in certain subtypes of von Willebrand disease. It results in the generation of two main fragments with apparent molecular masses of 140 kDa and 176 kDa from the 22...

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Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Dent, J A, Berkowitz, S D, Ware, J, Kasper, C K, Ruggeri, Z M
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1990
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54522/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2385594/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.16.6306
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