Rapid Throughput Analysis of GABA(A) Receptor Subtype Modulators and Blockers Using DiSBAC(1)(3) Membrane Potential Red Dye

Fluorometric imaging plate reader membrane potential dye (FMP-Red-Dye) is a proprietary tool for basic discovery and high-throughput drug screening for G-protein-coupled receptors and ion channels. We optimized and validated this potentiometric probe to assay functional modulators of heterologous ex...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Pharmacol
Prif Awduron: Nik, Atefeh Mousavi, Pressly, Brandon, Singh, Vikrant, Antrobus, Shane, Hulsizer, Susan, Rogawski, Michael A., Wulff, Heike, Pessah, Isaac N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Pharmacology and Experimental Therapeutics 2017
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452057/
https://ncbi.nlm.nih.gov/pubmed/28428226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.108563
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