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Rapid Throughput Analysis Demonstrates that Chemicals with Distinct Seizurogenic Mechanisms Differentially Alter Ca(2+) Dynamics in Networks Formed by Hippocampal Neurons in Culture
Primary cultured hippocampal neurons (HN) form functional networks displaying synchronous Ca(2+) oscillations (SCOs) whose patterns influence plasticity. Whether chemicals with distinct seizurogenic mechanisms differentially alter SCO patterns was investigated using mouse HN loaded with the Ca(2+) i...
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| Udgivet i: | Mol Pharmacol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366799/ https://ncbi.nlm.nih.gov/pubmed/25583085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.096701 |
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