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Transient transcription factor (OSKM) expression is key towards clinical translation of in vivo cell reprogramming

Reprogramming adult, fully differentiated cells to pluripotency in vivo via Oct3/4, Sox2, Klf4 and c‐Myc (OSKM) overexpression has proved feasible in various independent studies and could be used to induce tissue regeneration owing to the proliferative capacity and differentiation potential of the r...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: de Lázaro, Irene, Cossu, Giulio, Kostarelos, Kostas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452046/
https://ncbi.nlm.nih.gov/pubmed/28455313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707650
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