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Transient transcription factor (OSKM) expression is key towards clinical translation of in vivo cell reprogramming

Reprogramming adult, fully differentiated cells to pluripotency in vivo via Oct3/4, Sox2, Klf4 and c‐Myc (OSKM) overexpression has proved feasible in various independent studies and could be used to induce tissue regeneration owing to the proliferative capacity and differentiation potential of the r...

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Bibliografiska uppgifter
I publikationen:EMBO Mol Med
Huvudupphovsmän: de Lázaro, Irene, Cossu, Giulio, Kostarelos, Kostas
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452046/
https://ncbi.nlm.nih.gov/pubmed/28455313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707650
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