A carregar...

Non-viral, Tumor-free Induction of Transient Cell Reprogramming in Mouse Skeletal Muscle to Enhance Tissue Regeneration

Overexpression of Oct3/4, Klf4, Sox2, and c-Myc (OKSM) transcription factors can de-differentiate adult cells in vivo. While sustained OKSM expression triggers tumorigenesis through uncontrolled proliferation of toti- and pluripotent cells, transient reprogramming induces pluripotency-like features...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: de Lázaro, Irene, Yilmazer, Acelya, Nam, Yein, Qubisi, Sara, Razak, Fazilah Maizatul Abdul, Degens, Hans, Cossu, Giulio, Kostarelos, Kostas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318817/
https://ncbi.nlm.nih.gov/pubmed/30470628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.10.014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!