Molecular basis for Cdk1‐regulated timing of Mis18 complex assembly and CENP‐A deposition

The centromere, a chromosomal locus that acts as a microtubule attachment site, is epigenetically specified by the enrichment of CENP‐A nucleosomes. Centromere maintenance during the cell cycle requires HJURP‐mediated CENP‐A deposition, a process regulated by the Mis18 complex (Mis18α/Mis18β/Mis18BP...

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Udgivet i:EMBO Rep
Main Authors: Spiller, Frances, Medina‐Pritchard, Bethan, Abad, Maria Alba, Wear, Martin A, Molina, Oscar, Earnshaw, William C, Jeyaprakash, A Arockia
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Scientific Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452045/
https://ncbi.nlm.nih.gov/pubmed/28377371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643564
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