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Mild hypothermia preserves myocardial conduction during ischemia by maintaining gap junction intracellular communication and Na(+) channel function

Acute cardiac ischemia induces conduction velocity (CV) slowing and conduction block, promoting reentrant arrhythmias leading to sudden cardiac arrest. Previously, we found that mild hypothermia (MH; 32°C) attenuates ischemia-induced conduction block and CV slowing in a canine model of early global...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Nassal, Michelle M. J., Wan, Xiaoping, Dale, Zack, Deschênes, Isabelle, Wilson, Lance D., Piktel, Joseph S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451586/
https://ncbi.nlm.nih.gov/pubmed/28283549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00298.2016
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