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Cardioprotection by Mild Hypothermia During Ischemia Involves Preservation of ERK Activity

Cooling the ischemic heart by just a few degrees protects it from infarction without affecting its mechanical function, but the mechanism of this protection is unknown. We investigated whether signal transduction pathways might be involved in the anti-infarct effect of mild hypothermia (35°C). Isola...

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Detalhes bibliográficos
Main Authors: Yang, Xiulan, Liu, Yanping, Yang, Xi-Ming, Hu, Fangdi, Cui, Lin, Swingle, Mark R., Honkanen, Richard E., Soltani, Peyman, Tissier, Renaud, Cohen, Michael V., Downey, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638756/
https://ncbi.nlm.nih.gov/pubmed/21399968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-011-0165-0
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