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Prospective isolation of NKX2-1–expressing human lung progenitors derived from pluripotent stem cells

It has been postulated that during human fetal development, all cells of the lung epithelium derive from embryonic, endodermal, NK2 homeobox 1–expressing (NKX2-1(+)) precursor cells. However, this hypothesis has not been formally tested owing to an inability to purify or track these progenitors for...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Hawkins, Finn, Kramer, Philipp, Jacob, Anjali, Driver, Ian, Thomas, Dylan C., McCauley, Katherine B., Skvir, Nicholas, Crane, Ana M., Kurmann, Anita A., Hollenberg, Anthony N., Nguyen, Sinead, Wong, Brandon G., Khalil, Ahmad S., Huang, Sarah X.L., Guttentag, Susan, Rock, Jason R., Shannon, John M., Davis, Brian R., Kotton, Darrell N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451263/
https://ncbi.nlm.nih.gov/pubmed/28463226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI89950
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