mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell–derived hematopoietic progenitors

Generation of functional hematopoietic stem and progenitor cells (HSPCs) from human pluripotent stem cells (PSCs) has been a long-sought-after goal for use in hematopoietic cell production, disease modeling, and eventually transplantation medicine. Homing of HSPCs from bloodstream to bone marrow (BM...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Lee, Jungmin, Dykstra, Brad, Spencer, Joel A., Kenney, Laurie L., Greiner, Dale L., Shultz, Leonard D., Brehm, Michael A., Lin, Charles P., Sackstein, Robert, Rossi, Derrick J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2017
Matèries:
Brief Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451245/
https://ncbi.nlm.nih.gov/pubmed/28481220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92030
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