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Transcription factors SOHLH1 and SOHLH2 coordinate oocyte differentiation without affecting meiosis I

Following migration of primordial germ cells to the genital ridge, oogonia undergo several rounds of mitotic division and enter meiosis at approximately E13.5. Most oocytes arrest in the dictyate (diplotene) stage of meiosis circa E18.5. The genes necessary to drive oocyte differentiation in paralle...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Shin, Yong-Hyun, Ren, Yu, Suzuki, Hitomi, Golnoski, Kayla J., Ahn, Hyo won, Mico, Vasil, Rajkovic, Aleksandar
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451230/
https://ncbi.nlm.nih.gov/pubmed/28504655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90281
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