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Transcription factors SOHLH1 and SOHLH2 coordinate oocyte differentiation without affecting meiosis I

Following migration of primordial germ cells to the genital ridge, oogonia undergo several rounds of mitotic division and enter meiosis at approximately E13.5. Most oocytes arrest in the dictyate (diplotene) stage of meiosis circa E18.5. The genes necessary to drive oocyte differentiation in paralle...

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Pubblicato in:J Clin Invest
Autori principali: Shin, Yong-Hyun, Ren, Yu, Suzuki, Hitomi, Golnoski, Kayla J., Ahn, Hyo won, Mico, Vasil, Rajkovic, Aleksandar
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451230/
https://ncbi.nlm.nih.gov/pubmed/28504655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90281
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