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Transcription factors SOHLH1 and SOHLH2 coordinate oocyte differentiation without affecting meiosis I

Following migration of primordial germ cells to the genital ridge, oogonia undergo several rounds of mitotic division and enter meiosis at approximately E13.5. Most oocytes arrest in the dictyate (diplotene) stage of meiosis circa E18.5. The genes necessary to drive oocyte differentiation in paralle...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Shin, Yong-Hyun, Ren, Yu, Suzuki, Hitomi, Golnoski, Kayla J., Ahn, Hyo won, Mico, Vasil, Rajkovic, Aleksandar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451230/
https://ncbi.nlm.nih.gov/pubmed/28504655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90281
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