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CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice
A large proportion of human T cells are autoreactive to group 1 CD1 proteins, which include CD1a, CD1b, and CD1c. However, the physiological role of the CD1 proteins remains poorly defined. Here, we have generated a double-transgenic mouse model that expresses human CD1b and CD1c molecules (hCD1Tg)...
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| Pubblicato in: | J Clin Invest |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5451229/ https://ncbi.nlm.nih.gov/pubmed/28463230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92217 |
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