Načítá se...
How and when does an anticancer drug leave its binding site?
Obtaining atomistic resolution of drug unbinding from a protein is a much sought-after experimental and computational challenge. We report the unbinding dynamics of the anticancer drug dasatinib from c-Src kinase in full atomistic resolution using enhanced sampling molecular dynamics simulations. We...
Uloženo v:
| Vydáno v: | Sci Adv |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Association for the Advancement of Science
2017
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5451192/ https://ncbi.nlm.nih.gov/pubmed/28580424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1700014 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|