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Compliant substratum guides endothelial commitment from human pluripotent stem cells

The role of mechanical regulation in driving human induced pluripotent stem cell (hiPSC) differentiation has been minimally explored. Although endothelial cell (EC) fate from hiPSCs has been demonstrated using small molecules to drive mesoderm induction, the effects of substrate stiffness with regar...

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Bibliografische gegevens
Gepubliceerd in:Sci Adv
Hoofdauteurs: Smith, Quinton, Chan, Xin Yi, Carmo, Ana Maria, Trempel, Michelle, Saunders, Michael, Gerecht, Sharon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Association for the Advancement of Science 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451190/
https://ncbi.nlm.nih.gov/pubmed/28580421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1602883
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