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Compliant substratum guides endothelial commitment from human pluripotent stem cells

The role of mechanical regulation in driving human induced pluripotent stem cell (hiPSC) differentiation has been minimally explored. Although endothelial cell (EC) fate from hiPSCs has been demonstrated using small molecules to drive mesoderm induction, the effects of substrate stiffness with regar...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Smith, Quinton, Chan, Xin Yi, Carmo, Ana Maria, Trempel, Michelle, Saunders, Michael, Gerecht, Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451190/
https://ncbi.nlm.nih.gov/pubmed/28580421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1602883
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