Effect of Temperature on the Intrinsic Flexibility of DNA and Its Interaction with Architectural Proteins

[Image: see text] The helical structure of double-stranded DNA is destabilized by increasing temperature. Above a critical temperature (the melting temperature), the two strands in duplex DNA become fully separated. Below this temperature, the structural effects are localized. Using tethered particl...

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Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Driessen, Rosalie P. C., Sitters, Gerrit, Laurens, Niels, Moolenaar, Geri F., Wuite, Gijs J. L., Goosen, Nora, Dame, Remus Th.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451147/
https://ncbi.nlm.nih.gov/pubmed/25291500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500344j
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