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Comparison of single-marker and multi-marker tests in rare variant association studies of quantitative traits

In genetic association studies of rare variants, low statistical power and potential violations of established estimator properties are among the main challenges of association tests. Multi-marker tests (MMTs) have been proposed to target these challenges, but any comparison with single-marker tests...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Konigorski, Stefan, Yilmaz, Yildiz E., Pischon, Tobias
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451057/
https://ncbi.nlm.nih.gov/pubmed/28562689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178504
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