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Comparison of single-marker and multi-marker tests in rare variant association studies of quantitative traits

In genetic association studies of rare variants, low statistical power and potential violations of established estimator properties are among the main challenges of association tests. Multi-marker tests (MMTs) have been proposed to target these challenges, but any comparison with single-marker tests...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Konigorski, Stefan, Yilmaz, Yildiz E., Pischon, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451057/
https://ncbi.nlm.nih.gov/pubmed/28562689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178504
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