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Discovery and Characterization of the Tuberculosis Drug Lead Ecumicin
The new tuberculosis (TB) lead ecumicin (1), a cyclic tridecapeptide, was isolated from Nonomuraea sp. MJM5123, following a high-throughput campaign for anti-TB activity. The large molecular weight of 1599 amu detected by LC-HR-MS precluded the initial inference of its molecular formula. The individ...
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| 出版年: | Org Lett |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5450905/ https://ncbi.nlm.nih.gov/pubmed/25409285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol5026603 |
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