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Numb regulates somatic cell lineage commitment during early gonadogenesis in mice

During early gonadogenesis, proliferating cells in the coelomic epithelium (CE) give rise to most of the somatic cells in both XX and XY gonads. Previous dye-labeling experiments showed that a single CE cell could give rise to additional CE cells and to both supporting and interstitial cell lineages...

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Détails bibliographiques
Publié dans:Development
Auteurs principaux: Lin, Yi-Tzu, Barske, Lindsey, DeFalco, Tony, Capel, Blanche
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450849/
https://ncbi.nlm.nih.gov/pubmed/28360133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.149203
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