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Numb regulates somatic cell lineage commitment during early gonadogenesis in mice

During early gonadogenesis, proliferating cells in the coelomic epithelium (CE) give rise to most of the somatic cells in both XX and XY gonads. Previous dye-labeling experiments showed that a single CE cell could give rise to additional CE cells and to both supporting and interstitial cell lineages...

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Publicado en:Development
Autores principales: Lin, Yi-Tzu, Barske, Lindsey, DeFalco, Tony, Capel, Blanche
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450849/
https://ncbi.nlm.nih.gov/pubmed/28360133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.149203
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