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CDC42 is required for epicardial and pro-epicardial development by mediating FGF receptor trafficking to the plasma membrane

The epicardium contributes to multiple cardiac lineages and is essential for cardiac development and regeneration. However, the mechanism of epicardium formation is unclear. This study aimed to establish the cellular and molecular mechanisms underlying the dissociation of pro-epicardial cells (PECs)...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Li, Jingjing, Miao, Lianjie, Zhao, Chen, Shaikh Qureshi, Wasay Mohiuddin, Shieh, David, Guo, Hua, Lu, Yangyang, Hu, Saiyang, Huang, Alice, Zhang, Lu, Cai, Chen-leng, Wan, Leo Q., Xin, Hongbo, Vincent, Peter, Singer, Harold A., Zheng, Yi, Cleaver, Ondine, Fan, Zhen-Chuan, Wu, Mingfu
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450847/
https://ncbi.nlm.nih.gov/pubmed/28465335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.147173
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